Cerebellar cryptococcoma in a non-HIV patient.

A 26-year-old female, immunocompetent, with dysmetria and dysarthria. Diagnostic imaging (Fig 1) demonstrated a cerebellar mass, with a pattern which may be associated to a tumor, although multiple hypointense centers surrounded by ring enhancement after gadolinium may suggest the possibility of many types of infectious lesions, including cryptococcoma. Histological analysis (Fig 2) confirmed the diagnosis of Cryptococcus neoformans. Central nervous system cryptococcosis is rare in immunocompetent individuals and is considered an opportunistic pathogen in AIDS patients. In immunocompetent individuals, cryptococcoma is the most common form of cerebral involvement. This patient had a good outcome after surgery and anti-fungal therapy.